Reconstructing genome-scale metabolic models with merlin
نویسندگان
چکیده
منابع مشابه
Reconstructing genome-scale metabolic models with merlin
The Metabolic Models Reconstruction Using Genome-Scale Information (merlin) tool is a user-friendly Java application that aids the reconstruction of genome-scale metabolic models for any organism that has its genome sequenced. It performs the major steps of the reconstruction process, including the functional genomic annotation of the whole genome and subsequent construction of the portfolio of...
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This article describes Merlin, a user-friendly program that performs functional genomic annotations of lists of genes. Merlin retrieves information of each homologue and automatically scores the results, allowing the user to change the score selection, and dynamically (re-)annotate the genome. Merlin expedites the transition from genome-scale data to SBML metabolic models, allowing the user to ...
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Reconstructing a model of the metabolic network of an organism from its annotated genome sequence would seem, at first sight, to be one of the most straightforward tasks in functional genomics, even if the various data sources required were never designed with this application in mind. The number of genome-scale metabolic models is, however, lagging far behind the number of sequenced genomes an...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2015
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkv294